Scientific topics
Keywords
frederic saltel Invadosome involvement in liver diseases.
Course and current status
RESEARCH EXPERIENCE
Since 2008 CR1 INSERM U-1053 (ex U-889), Bordeaux 2, Team 2 from Dr. J. Rosenbaum
Research projects:
Involvement of linear invadosomes in liver diseases.
2006 - 2008 CDD INSERM U-889 (IECB) - European Institute of Chemistry and Biology - Dr. Génot Team. Director J. Rosenbaum.
Pathophysiology of hepatic sinusoidal endothelial cells: analysis of the actin cytoskeleton.
2004 - 2006 Postdoctoral (University of Geneva) - Medical Center University - Team Dr. Wehrle-Haller.
Interaction between talin and integrin αvβ3. (EMBO Fellowship 2006).
2001 - 2004 PhD in Biology from the bones (University Paris VII) - Ens de Lyon - LBMC - PhD Director : Dr. Pierre Jurdic.
Evolution and dynamics of actin cytoskeleton differentiation to osteoclastic resorption.
Scientific summary
Cell-extracellular matrix interactions (Frederic Saltel)
The group studies actin structures related to invadosomes allowing interaction of cells with extracellular matrix and their role in adhesion, degradation and cell invasion in hepatocellular carcinoma (HCC).
