• E-mail :[email]
  • Phone : +33 4 72 68 19 30
  • Location : Lyon, France
Last update 2012-11-15 09:12:32.023

David Melodelima PhD Biomedical Engineering

Course and current status

Academic record

Ph.D. Biomedical Engineering, 2004, University Claude Bernard Lyon I
MS Physics, 2001, University Claude Bernard Lyon I
BS Physics, 2000, University Claude Bernard Lyon I


Work experience

2005 – Today: Scientist
French Institute of Health and Medical Research, unit 556, Lyon, France.
Treatment of liver metastasis using high intensity focused ultrasound.

2004 – 2005: Postdoc
Joint Department of Physics, Institute of Cancer Research and Royal Marsden Hospital NHS Trust, Sutton, Surrey, UK.
Radiation force elastography – automated breast imaging.

2001 – 2004: PhD student
French Institute of Health and Medical Research, unit 556, Lyon, France.
Intraluminal ultrasound applicator with electronic beam steering for oesophagus tumour ablation under MRI guidance: Optimization of the coagulated depth by combination with cavitation.

Scientific summary

High intensity focused ultrasound (HIFU) has proved to be highly efficient in inducing homogeneous and reproducible tumor destruction by thermal coagulation necrosis, both experimentally and clinically. This method is receiving increased attention due to the capabilities of ultrasound imaging and magnetic resonance imaging to provide guidance and monitoring. HIFU seems to be an appropriate potential alternative to conventional therapies for the treatment of liver metastases but its use needs to be experimentally tested in vivo. It is plan to establish new procedures for selective tissue destruction with HIFU and targeting with ultrasound imaging. The long-term objective is to develop a device that can be used during surgery for eventual clinical use in conjunction with resection.

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