Philippe Van de Perre MD, PhD, Medical Biology
Course and current status
Present position:
Professor of medicine (PUPH, 1ère classe), University Montpellier 1
Head of Department Bacteriology-Virology, University Teaching Hospital (CHRU) Montpellier
Director INSERM U 1058 "Infection by HIV and by agents with mucocutaneous tropism: from pathogenesis to prevention"
Age : 55 years
PROFESSIONAL EXPERIENCE:
- From 1st December 2000-present position: Head of department bacteriology-virology, University Teaching Hospital, and from Jan 2011: director research unit INSERM U 1058 (University Montpellier 1/INSERM/CHU Montpellier)
- 1995-2001: Director of the Centre Muraz (Regional medical research centre), Burkina Faso
- 1985-1995: Director of the National AIDS Reference Laboratory, Rwanda.
- 1984-1985: Assistant in the laboratory of microbiology, WHO collaborating center, Saint-Pierre University Hospital, Brussels, Belgium
- 1983-1984: Fellowship in infectious diseases and clinical microbiology, Free University Brussels, Brussels, Belgium.
Scientific summary
Management activities:
Vice President (in charge of research) of the CHRU Montpellier Directorate
Member of the Scientific Committee, Faculty of Medicine, University Montpellier 1
Coordinator of the ANRS programme in Burkina Faso
Member the ANRS Coordinated Action # 12 (AC12) « developing countries
Member the ANRS Coordinated Action # 11 (AC11) «medical virology »
Expert at the NIH/NIAID Viral Pathogenesis Review Committee
Expert at ANR Microbiology review panel
President of the Scientific Committee "AIDS, health and development", Fondation de France
Member of the Scientific Committee of the Institute of Tropical Medicine, Antwerp, Belgium
Member of the organizing or scientific committee of 25 international AIDS conferences
Member of the editorial board of AIDS
Invited presentations to international conferences:
Invited speaker to 34 international meetings
TEACHING:
Medical Students, Faculty of Medicine, University Montpellier 1
Master 1 & 2 (BioMed, UM1/UM2, coordinator of a teaching unit)
University diplomas.
PUBLICATIONS:
Author of 317 articles in peer reviewed scientific journals. Sum of times cited: 9,110 (July 2010). H-index: 51
10 more significant publications:
1. Van de Perre P, Rouvroy D, Lepage P, Bogaerts J, Kestelyn P, Kayihigi J, Hekker AC, Butzler JP, Clumeck N. Acquired immunodeficiency syndrome in Rwanda. Lancet 1984; ii: 62-5.
2. Van de Perre P, Clumeck N, Carael M, et al. Female prostitutes: a high risk group for infection with the Human T-cell Lymphotropic Virus type III. Lancet 1985; ii: 524-7.
3. Van de Perre P, Simonon A, Msellati P, et al. Postnatal transmission of human immunodeficiency virus type 1 from mother to child. A prospective cohort study in Kigali, Rwanda. New Engl J Med 1991; 325: 593-8.
4. Van de Perre P, Simonon A, Hitimana DG, et al. Infective and anti-infective properties of breast milk from HIV-1 infected mothers. Lancet 1993; 341: 914-8.
5. Van de Perre P. Mother-to-child transmission of HIV-1 : the “ all mucosal ” hypothesis as a predominant mechanism of transmission. AIDS 1999; 13: 1133-38.
6. Manigart O, Crépin M, Leroy V, Meda N, Valéa D, Janoff E, Rouet F, Dequae Merchadoux L, Dabis F, Rouzioux C, and Van de Perre P for the DITRAME Study Group. Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 in breast milk and on postnatal transmission. J Infect Dis 2004; 190:1422-8.
7. Becquart P, Petitjean G, Al Tabaa Y, Valéa D, Huguet MF, Tuaillon E, Meda N, Vendrell JP and Van de Perre P. Detection of a large T cell reservoir able to replicate HIV-1 actively in breast milk. AIDS 2006; 20: 1453-5.
8. Nagot N, Ouedraogo A, Foulongne V, Konate I, Weiss HA, Vergne L, Defer MC, Djagbare D, Sanon A, Andonaba JB, Becquart P, Segondy M, Vallo R, Sawadogo A, Van de Perre P, Mayaud P. Reductions in genital and systemic HIV-1 RNA in coinfected women with Herpes simplex virus type 2 (HSV-2) suppressive therapy: a randomized placebo-controlled trial. N Engl J Med 2007; 356: 790-9.
9. Van de Perre P, Nagot N, Foulongne V, Ouedraogo A, Konate I, Huraux JM, Mayaud P and Segondy M. Herpes simplex virus and Human Immunodeficiency Virus: deciphering a viral synergy. Lancet Infectious Diseases 2008; 8: 490-7.
10. Tuaillon E & Valéa D, Becquart P, Al Tabaa Y, Meda N, Bolloré K, Van de Perre P, Vendrell JP. Human milk-derived B cells: a highly activated switched memory cell population primed to secrete antibodies. J Immunol 2009; 182: 7155-62.
