CV Science

Valériane Leroy Research Director, MD, PhD

Course and current status

I am Research Director in Epidemiology and Public Health, at Inserm since 2005.  I am MD (1993, Bordeaux University), phD epidemiologist (1996, Bordeaux University), involved in the prevention of mother-to-children transmission research in Africa during 15 years, and now responsible of the pediatric research program since 2005, within the team on HIV and global health in Africa at the Inserm U897, Bordeaux School of Public Health in Bordeaux, France.

I will join the Inserm U1027 team in Toulouse, France in 2016, as responsible of a research axis on pediatric infectious diseases in Africa. I have a specific interest in maternal and child health in low-income countries, especially in West-Africa.

To date my research has focused on HIV. My main research interests are the burden of this infection in women and during pregnancy, mother-to-child transmission and its prevention, treatment and outcomes in HIV infected children.

Scientific summary

I am currently principal investigator of the MONOD ANRS 12206 clinical trial (ClinicalTrial.gov registry number: NCT01127204), including post-randomization data comparing a switch from lopinavir/ritonavir-based ART to efavirenz-based ART to remaining on suppressive lopinavir/ritonavir-based ART, and pre-enrollment data on the cascade of care from early infant diagnosis to ART initiation.

I am the scientific responsible of the pediatric International epidemiological Database on IeDEA West African paediatric cohort (pWADA) since 2006, providing clinical and health resource utilization data for HIV-exposed children, ART-naive children, and ART-treated children from the IeDEA West African cohort (7 countries).

I am a pediatric HIV expert for new issues in Côte d’Ivoire and West Africa to address questions of critical importance in Côte d'Ivoire, and to use the best, most recent clinical, public health and economic data.