Professional Training: University Montpellier II “Sciences & Technologies”
Master « Integrative Physiology » (1980)
Ph.D. “Endocrinology” (1983)
Agreement for Ph.D. training (Habilitation à Diriger des Recherches - 1994)
Postdoctoral Position: Department of Medicine, Monash University, Australia (Dec 1985 to June 1987), Pr. Colin Johnston - Pr. Barry McGrath
Position : Senior Research, Institut National de la Santé et de la Recherche Médicale –INSERM since 1989
EA 3127 “Groupe Rein & Hypertension”, University Montpellier I, Faculty of Medicine 1989-2010
CNRS-FRE3400 “Centre innovation & Pharmacology Diabetes” Montpellier 2011-
In charge of animal house (n°b-34-172-26, arrêté 03 XIX 55)
Agreement for animal experimentation (rat, mouse, rabbit): 34.179 (December 2008-2013)
The field of interest is the cardiovascular and renal alterations in various pathological states with or without an increase in arterial pressure. The aim is to evaluate the impact and interaction of risk factors, including life style modifications (exercise, dietary sodium modulation), hormonal status (renin-angiotensin-aldosterone system, nitric oxide, endothelin) and metabolic factors (oxidative stress, glycemia, lipidemia). Pathologies studied are hypertension, insulino-resistance, obesity (metabolic syndrome). Expertise was developed in cardiac and vascular hypertrophy, angiogenesis, renal function and sodium handling. Morphological structure determination involved histological approach, cardiac vascular density determination, arterial and cardiac pressures measurement, renal hemodynamic study (Transonic). Ex vivo angiogenesis technique (adapted from Nicosia) can be realized from various vessels (aorta, renal, mesenteric, and coronary arteries).