- E-mail :[email]
- Phone : +33 3 72 74 61 35 (std)
- Location : INSERM U1256 - NGERE, Vandoeuvre-lès-Nancy, France
Scientific topics
Keywords
ITMO
Jean-Noel Freund PhD, Molecular and Cellular Biology
Course and current status
Current Position
Inserm U1256 / NGERE – Lorraine University (2024 - current) Senior Scientist « Nutrition, Genetics and Environment Risks Exposure »
Career
PhD, University Louis Pasteur, Strasbourg (1986): « Structural and Functional Organization of the rudimentary locus of Drosophila melanogaster » (supervisor: Prof. P Chambon, Inserm U184 / LGME)
Inserm U61 (1987 – 1992): Junior Scientist - Team « Intestinal Lactase »
Inserm U381 (1993 – 2004): Team Leader « Genetic regulation of intestinal differentiation; Lactase »
Inserm U682 (2005 – 2012): Team Leader « Transcription Factors and Signaling Pathways in Development, Homeostasis and Pathology of the Digestive Tract »
Inserm U682 (2012): Acting Director « From Tissue Homeostasis to Inflammation and Cancer »
Inserm UMR-S1113 / IRFAC (2013 – 2023): Director « Interface between Fundamental and Applied Cancer Research » ; Team Leader " Stem Cell Emergence and Tumor Initiation"
Scientific summary
Research area
>> Pyrimidine pathway in Drosophila melanogaster
>> Intestinal Lactase - Hypolactasia
>> Development, homeostasis and cancer of the digestive tract - CDX homeobox genes
>> Hematopoietic emergence and leukemia - CDX homeobox genes
>> One-carbon metabolism in Cancer Stem Cells
