CV Science

Sylvie Claeysen PhD Molecular Neuroscience & Pharmacology

Course and current status

CURRENT POSITION

INSERM Senior Researcher – Project leader

EDUCATION

• 2009: Qualification to supervise Ph.D. theses (HDR), University of Montpellier, France

• 1999: PhD – University of Montpellier, France
  

POSITIONS HELD

•  2023-       : INSERM Senior Researcher - Hors Classe, Institute of Functional Genomics (IGF), Montpellier, France

• 2006-2022: INSERM Senior Researcher, Institute of Functional Genomics (IGF), Montpellier, France

• 2002-2006: INSERM Junior Researcher, Laboratory of Functional Genomics (LGF), Montpellier, France

• 2000-2002: Post-doctoral fellow, Institute of Interdisciplinary Research in Human and Molecular Biology (IRIBHM), Bruxelles, Belgium

Scientific summary

Sylvie Claeysen is an expert in neuropharmacology, G protein-coupled receptors (GPCR), serotonin receptors and neurodegenerative disorders. In connection with a network of clinicians, chemists, and biotech companies, she proposes innovative strategies to cure Alzheimer's disease (α-secretase activation, Multi-Targeted drugs, biomarkers), based on a deep knowledge of molecular and cellular mechanisms induced by GPCRs in neuroprotection. She was a member of the Scientific Council of France Alzheimer from 2015 to 2023, and of Inserm's cross-cutting Program "Microbiota" from 2016 to 2025. She is currently a partner in the targeted PREANALYTICS project of the national "Food Systems, Microbiomes and Health" program (PEPR SAMS), and co-leader of the MICMALZ clinical study. In this context, she is exploring the potential of modulating the gut microbiota as a new approach to the prevention and treatment of Alzheimer's disease.

MAJOR GRANTS

• 2025-2029: Fundation for Medical Research, FRM MND, Co-PI
• 2025-2029: French National Research Agency, ANR MICROCONNECT, Partner
• 2025-2027: France Alzheimer, Coordinator
• 2024-2028: National PEPR SAMS (PREANALYTICS), Partner
• 2023-2026: French National Research Agency, ANR DENTALCOG, Partner
• 2021-2024: French National Research Agency, ANR DOWNALZ, Partner
  
• 2019-2022: Région Occitanie/FEDER Project MICMALZ, Coordinator
• 2017-2024: Inserm cross-cutting Program Microbiota, Partner
• 2016-2019: Ligue Européenne Contre la Maladie d'Alzheimer, L.E.C.M.A., PI
• 2015-2018: Fondation Plan Alzheimer, Partner
  
• 2015-2018: Fédération pour la Recherche sur le Cerveau, FRC, Partner
  
• 2013-2018: French National Research Agency, ANR ADAMGUARD
  
• 2012-2014: Ligue Européenne Contre la Maladie d'Alzheimer, L.E.C.M.A., PI
• 2012-2015: Région Languedoc-Roussillon, PI
• 2011-2014: France Alzheimer association, PI
• 2004-2006: Fondation de France, PI

HONORS

• 2024-26: Research and Doctoral Supervision grant (PEDR)
• 2020-23: Research and Doctoral Supervision grant (PEDR)
• 2013: Junior Faculty Award – AD/PD™ 2013 - The Alzheimer's & Parkinson's Conference
• 2012: "Chercheuse d'avenir" of the Languedoc Roussillon Region
• 2011: Soroptimist International (French Union) medal
• 2010: 2010 Research Prize of the France Alzheimer association
• 1997: Roche Bioscience Prize  – Advances in Serotonin Receptor Research, San Francisco, USA.