Pierre Layrolle
  • E-mail :[email]
  • Phone : +33 2 72 64 11 43
  • Location : Nantes, France
Last update 2014-09-01 09:33:25.618

Pierre Layrolle Bone tissue engineering and biomaterials

Course and current status

Current position:

INSERM Director of research (DR1) 

INSERM U957, Lab. of pathophysiology of bone resorption, Faculty of Medicine, University of Nantes

Coordinator of the European project www.reborne.org that uses mesenchymal stem cells and biomaterials to regenerate bones in 5 clinical trials.


Previous experience: 

1991-1994     PhD in Biomaterials at the Engineering School of Chemistry of Toulouse. Synthesis of calcium phosphates in organic solvents. Director: Prof. Christian Rey

1995-1997     Post-doctoral researcher in Tsukuba (Japan). Preparation and biological study of Zinc-substituted hydroxyapatite bioceramics. Director: Dr. Atsuo Ito

1997-2002       Senior Research Scientist at ISOTIS Orthobiologics SA (The Netherlands) Head of the bioceramics group, Directors: Profs. Klaas de Groot and Clemens van Blitterswijk

2002-2003   Head of the Materials Department; Technology transfer centre, Le Mans

2003-2007     Senior researcher (CR1) at INSERM, Nantes. Bone tissue engineering

2007-2012    Director of research (DR2) at INSERM, Nantes. Bone tissue engineering

2010-now      Co-founder of the spinoff company BIOMEDICAL TISSUES  www.biometiss.com. Invention of synthetic extracellular matrix.

Scientific summary

Pierre Layrolle has extensive experience in tissue engineering research both in industry and academia. He obtained his PhD in biomaterials in 1994 at the Polytechnic National Institute of Toulouse (FR) and his thesis was awarded the Leopold Escande prize. He completed his postdoctoral studies in Japan and later joined the tissue engineering company IsoTis (NL) prior to enter INSERM in Nantes.

He is currently the coordinator of the FP7 REBORNE project, aimed at regenerating bone defects using a combination of stem cells and biomaterials. This project gathers 24 partners in 8 European countries, including research labs, hospitals, biomaterial companies, and cell manufacturing facilities. His team has conducted a vast amount of pre-clinical studies and 5 clinical trials are currently underway which show excellent results and this work is routinely highlighted in national and international media.

Pierre Layrolle is inventor of 14 patents, authored over 130 peer-reviewed publications, member of the Editorial board of several journals (Acta Biomaterialia, Biomedical Materials, J Mater Sci Mater Med, The Open bone journal) and regularly invited to present at international conferences. He has also organized several conferences such as the European Society for Biomaterials in 2006, Bioceramics 20 in 2007 and the European Orthopaedic Research Society conference in 2014. 

Image d’exemple