Stéphane Jamain
  • E-mail :[email]
  • Phone : +33 1 49 81 37 75
  • Location : Créteil, France
Last update 2011-05-26 09:54:24.141

Stéphane Jamain Ph.D. Human Genetics

Course and current status

Current position:
Since June 2005: tenure position as researcher (“chargé de recherche 1ère classe” equivalent to Associate Professor) at Institut National de la Santé et de la Recherche Médicale (INSERM, Créteil, France).
Institut Mondor de Recherche Biomédicale (IMRB, INSERM U955, Director: Prof Georges Guellaen), EQ15 “Psychiatry Genetics”, Director: Prof Marion Leboyer, Henri Mondor Hospital, Créteil, France.

Other Experience and Professional Memberships:
1999 - 2003: Ph.D. in Human Genetics, "Identification of susceptibility genes to autism an dschizophrenia", Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France, Director: Prof Thomas Bourgeron.

2003 – 2005: Postdoctoral fellowship in Neuroscience, "Study of neuroligins in mice as animal model for autism", Max-Planck Institute for Experimental Medicine, Göttingen, Germany, Director: Prof Dr Nils Brose.

2005 – 2007: Laboratory of Psychiatry and Neurobiology, INSERM U 513, Faculté de Médecine-Hôpital Henri Mondor, Créteil, France. Director: Prof Bruno Giros.

Scientific summary

Stéphane Jamain obtained a Ph.D. in Human Genetics in the Thomas Bourgeron’s lab at the Pasteur Institute (Paris, France), during which he identified the first functional mutations involved in idiopathic autism in the genes encoding neuroligins. These findings led to the identification of a physiological mechanism altered in autism spectrum disorders. Then, he got an EMBO long-term fellowship to achieve a postdoc in the Prof. Nils Brose’s lab at the Max-Planck Institute of Experimental Medicine (Göttingen, Germany) to generate a mouse strain, mutant for neuroligin 4. These mice showed a phenotype reminiscent of two of the three cardinal symptoms of autism, with deficits in social interactions and decreased vocalizations. In 2005, Stéphane Jamain obtained a tenure position at Inserm and joined the group of Prof. Marion Leboyer (Inserm U955, EQ15) in which he is in charge of a team working on genetical and molecular biological aspects of bipolar disorder and schizophrenia. He is also responsible for coordinating the DNA library of the National Network of Expert Centres on Bipolar Disorder, Schizophrenia and Asperger syndrome of the FondaMental Foundation (dir. Prof. Marion Leboyer).

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